The SAGE Trial

Supplementation in Adolescent Girls with Endometriosis (The SAGE Study) is a six-month research study that explores the effect of nutrition on the development and severity of the symptoms of endometriosis. Participants take 2 pills every day (dietary supplement or a placebo pill) to help us study whether these supplements help improve pain and other endometriosis symptoms.

Research study participants are asked to:

  • Make three study visits to the Clinical and Translational Study Unit (CTSU) at Boston Children’s Hospital
  • Take two study medications daily for 6 months – dietary supplements and/or placebo pills
  • Give blood samples, have vital signs (for example, your blood pressure, pulse) taken, and complete questionnaires about medicines, symptoms, and quality of life
  • Describe your usual diet at each visit

This study is not currently recruiting. For additional information, please email